MYELOID NEOPLASIA WT1 mutation in 470 adult patients with acute myeloid leukemia: stability during disease evolution and implication of its incorporation into a survival scoring system
نویسندگان
چکیده
1Division of Hematology, Department of Internal Medicine, National Taiwan University Hospital, Taipei; 2Department of Clinical Laboratory Sciences and Medical Biotechnology, College of Medicine, National Taiwan University, Taipei; 3Biostatistics Consulting Laboratory, Department of Nursing, National Taipei College of Nursing, Taipei; and Departments of 4Laboratory Medicine and 5Pathology, National Taiwan University Hospital, Taipei, Taiwan
منابع مشابه
WT1 mutation in 470 adult patients with acute myeloid leukemia: stability during disease evolution and implication of its incorporation into a survival scoring system.
The impact of WT1 mutations in acute myeloid leukemia (AML) is not completely settled. We aimed to determine the clinical implication of WT1 mutation in 470 de novo non-M3 AML patients and its stability during the clinical course. WT1 mutations were identified in 6.8% of total patients and 8.3% of younger patients with normal karyotype (CN-AML). The WT1 mutation was closely associated with youn...
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تاریخ انتشار 2010